Women with a common hormonal disorder have few good treatment options. Could GLP-1 drugs help?

Ozempic and GLP-1 drugs like it became household names due to their potent weight loss benefits, and are now proving useful in a slew of other chronic conditions.

Women are noticing other benefits, too, including some that may be flying under pharmaceutical companies’ radars. Reports have emerged of unexpected pregnancies among women on GLP-1 treatment, and researchers have mused of possible effects on fertility or on hormonal disorders as well.

Melanie Cree, a pediatric endocrinologist at Children’s Hospital Colorado, is one physician looking into this question. Working with her colleagues, she conducted a randomized trial testing semaglutide, the ingredient in Novo Nordisk’s Rybelsus and Wegovy, in women and adolescents with polycystic ovary syndrome, or PCOS.

Cree said this research “provides evidence of what these medications can do for PCOS, reproductive measures and periods specifically.” While results from Cree’s first trial aren’t yet published, they were encouraging enough…
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